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Bacillus Expression System
Among prokaryotic expression systems, the E. coli system is the most widely used due to its simplicity, low cost, and well-established protocols. However, its major limitation is that target proteins are typically confined to intracellular or periplasmic expression, with secretion being inefficient even when using signal peptides.
As a Gram-positive bacterium, Bacillus offers distinct advantages for recombinant protein production, including efficient secretion of exogenous proteins, lack of inclusion body formation, and non-pathogenicity. These attributes make it an ideal host for protein expression and secretion within prokaryotic systems. As a result, Bacillus has become a key model organism for prokaryotic expression, successfully producing various industrial enzymes and recombinant proteins.
Service Process
Service Advantages
We has rich experience in protein expression in Bacillus subtilis and can provide a variety of expression vectors and strains to meet different protein expression needs. Meanwhile, we provide one-stop flexible service from codon optimization to recombinant protein expression, purification, de-endotoxin, etc., which can meet different customized needs of customers.
Tel：+86 4008677715
E-mail：service@nb-biolab.com
Address：SME Incubation Park, 319 Qingpi Avenue, Chengdu, China.
Working time：9:00-18:00