Antibody Humanization
Single domain antibodies (sdAb) offer exceptional advantages for biotechnological and medical applications due to their stable structure, ease of production, excellent water solubility, high affinity towards antigens, and low immunogenicity. Despite the remarkable human-like sequence and structure of camelid antibodies, the potential immunogenicity arising from their non-human origin remains a significant concern in therapeutic applications. Consequently, single domain antibody humanization constitutes a critical step in the therapeutic antibody discovery process.
Leveraging our extensive experience in sdAb development and downstream engineering, NBbiolab provides tailored solutions to generate novel humanized single domain antibodies, guaranteeing high throughput characterization, short turnaround times, and affinities and functional activities that meet our clients' expectations.
Why Choose NBbiolab for your monoclonal antibody humanization?
Case Stastics: C6-HZ (humanized VHH)