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LOCATION: Home>Products>Large Naïve VHH library>Phage display based Naïve VHH Library from llama
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Large Naïve VHH library

Phage display based Naïve VHH Library from llama

Category: Large Naïve VHH library

Product overview Documents References FAQ

The preparation of single domain antibody libraries starting from lymphocytes recovered from immunized members of the Camelidae enables to collect binders that underwent somatic maturation. However, the time and costs necessary to prepare a library for each new antigen may urge to look for alternatives such as those offered by large one-pot libraries. 


Here we constructed five large naïve libraries using PBMCs  from 20 healthy nonimmunized llamas.The library consists of 1010 individual transformants with more than 90 % unique sequences and  the positive insert ratio was more than 99.99%. We leverage this established library along with our advanced screening platform to extend the epitope coverage and help clients find the optimal monoclonal antibody candidates Despite the lack of somatic maturation, the selection based on phage display allowed to isolate from such naïve libraries VHHs with affinity in the subnanomolar range and suitable for the standard immune applications. 

Cat / Size / Price

LlaSDAb(P) - 500μL / 询价

Contact

If you want to sell VHH on our platform, please contact us !

Phone

13551086942

Email

service@nb-biolab.com

INFORMATION

E-mail:service@nb-biolab.com


Address:Wenjiang, Chengdu, Sichuan, China


Working time:9:00-18:00


CONTACT

Phone:400-166-9953

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